Metforminassociated lactic acidosis is a rare but important etiology of lactic acidosis. Acidosis lactica trastornos endocrinologicos y metabolicos. At clinical presentation, several causes usually can be identified. Algunas enfermedades tambien pueden causar esta afeccion, incluyendo. Get a printable copy pdf file of the complete article 2. Full text full text is available as a scanned copy of the original print version. Lactic acid accumulates in the system when oxygen level in the body drops. Links to pubmed are also available for selected references. We present the case of a patient with hypertension treated with indapamide and captopril and type 2 diabetes mellitus treated with insulin and metformin. Elevated plasma metformin concentrations as occur in individuals with renal impairment and a secondary event or condition that further disrupts lactate production or clearance e. Lactic acidosis is a clinical condition where there is an active accumulation of lactic acid in the serum.